235 Citrus Tower Blvd.
Clermont, FL. 34711
Phone: (863) 419-0104
40124 US Hwy 27, Suite 202
Davenport, FL 33837
Phone: (863) 419-0104
1121 North Central Ave, Suite B.
Kissimmee, Fl. 34741
Phone: (407) 933-1221

Clinical Research

Got Phlegm?

Did you know that PDS Research is currently conducting several clinical research trials for new pulmonary medications? If your present medications are not providing adequate treatment, clinical research may be an alternative! PDS treats may conditions which are listed below. If you or a loved one has one of the following pulmonary or sleep conditions, there may be current or pending studies for which you may qualify:

  • ASTHMA
  • COPD
  • BRONCHIECTASIS
  • PULMONARY HYPERTENSION
  • CHRONIC LUNG INFECTIONS
  • PULMONARY FIBROSIS
  • Lung Nodules
  • Narcolepsy
  • Sarcoidosis

Your participation could not only benefit yourself, but millions of people affected with pulmonary and sleep conditions. You will also receive compensation for time and travel.

Please call our office at 407-624-4831 for more information!!!

FOR PATIENTS:

Volunteering for a clinical research study is a very important decision and it’s important that you are informed every step of the way. At PDS, we would like to provide you with information that would be helpful in making the right decision.

What is clinical research?
Clinical Research is a study in which volunteers receive investigational medication to determine the safety and efficacy of a new products intended for human use. These studies are supervised by medical doctors and trained research professionals which include study nurses, coordinators and respiratory therapists who are at your service to ensure your safety while participating in the study.

How do I qualify for a study?
Each clinical study has specific criteria to partake in a study. These specifics are called inclusion/exclusion criteria. These criteria can be based upon age, severity of your condition, medical history or even specific medications you are presently taking. Each study is different, and we will be happy to review all aspects of your medical condition with you to see if you would qualify.

What happens during the study?
The first and foremost procedure conducted is to inform you about the study prior to participation. The study doctor and nurse will review the aspects of what is called “The Informed Consent.” This consent will go into detail about the length of the study, the study design, risks involved with the study and your responsibility in participating. It will also review the types of safety procedures which will occur during your participation to ensure the health and welfare of each participant. These procedures may include vital signs, electrocardiogram, blood work, pulmonary function testing, etc…

What are the benefits of participating in a clinical trial?
You may benefit from participating by being provided therapies that may offer alternative treatment options and even possible cures for chronic diseases. Study medication and procedures performed during the course of the study are at no cost to you or your insurance. You also may be compensated for your time and travel during participation.

How do I volunteer?
You may call our office at 407-624-4831 or email our Site Director at mbell@pds-cfsc.com to inquire about the types of studies and your interest in participating. We look forward to hearing from you!

FOR SPONSORS/CRO’S:

Pulmonary Disease Specialists, PA, d/b/a PDS Research has been in operation since 2005 under the direction of President and Principal Investigator, Thomas W. O’Brien, MD. Dr. O’Brien has been a practitioner for over 20 years. He is dedicated to introducing new treatment alternatives through the research process that will help in improving the quality of life for patients living with pulmonary diseases and sleep medicine.

PDS Research is a dedicated clinical research facility within a multi-physician, pulmonary practice in Kissimmee, Florida. PDS has conducted Phase II-IV and device studies since 2007. We have an accredited sleep center which also allows us to conduct overnight trials. Our site employs highly dedicated and experienced staff which produces consistency, compliance, and the highest quality performance on your trial, all the while ensuring the rights, welfare and safety or our trial participants.

Several advantages to our site include:

  • Timely turnaround of regulatory documents
  • Complete set of SOP’s
  • Current GCP and IATA training of all staff
  • Excellent patient compliance and retention
  • Central IRB’s utilized (no local IRB’s needed)
  • 9 Physicians and 4 Nurse practitioners serving three private practice locations
  • Access to thousands of patients in our database


Our facilities at PDS includes manual and automated vital sign apparatus, pulse ox, temperature device, temperature controlled refrigerator and -20 freezer, all of which are calibrated annually. Our independent, locked, ambient drug room stores investigational product. We have two large rooms for monitoring visits with access to WIFI. We have multiple rooms to utilize for informed consent and study visits. PDS also has two independent rooms to conduct pulmonary function testing to include DLco and arterial blood gases. We also facilitate an accredited state-of-the-art sleep center which can house multiple patients and can be utilized for overnight and inpatient studies.

Our site experience includes working with many sponsors, CRO’s and vendors to include Pfizer, Pearl Therapeutics, Astra Zeneca, Otsuka Pharmaceuticals, Array Pharmaceuticals, Gilead Sciences, Paraxel, Inventiv Health, PPD, INC Research, PRA International, and many more. We have also worked with vendors to include Perceptive, iMedidata, CTMS, RAVE, InForm, datalabs, Covance, ICON, Acurian and many others. Our commitment to providing our sponsors and vendors with the highest quality data is our goal. Our mission is to provide our volunteers with the latest and most effective alternatives while assuring their safety while participating in these trials.

To receive additional information or to contact our site for participation in an upcoming clinical trial, please contact our Site Director, Margaret Bell, at 407-624-4831 or email at mbell@pds-cfsc.com.



Current enrollling studies:

  • COPD
  • Pulmonary Hypertension
  • Pulmonary Fibrosis
  • Lung Nodules
  • Narcolepsy
  • Flu study
  • Alpha 1 Deficiency